Human molecular genetics /
Tom Strachan and Andrew P. Read.
- Oxford : New York : BIOS Scientific Publishers Wiley-Liss, 1996.
- xiv, 597 pages : illustrations (some color) ; 28 cm.
Includes bibliographical references and index.
1. DNA structure and function -- 2. Chromosome structure and function -- 3. Genes in pedigrees -- 4. Cell-based DNA cloning -- 5. DNA hybridization assays -- 6. PCR-based DNA cloning and DNA analyses -- 7. Organization and expression of the human genome -- 8. Human multigene families and repetitive DNA -- 9. Footprints of evolution -- 10. Mutation and instability of human DNA -- 11. Physical mapping -- 12. Genetic mapping -- 13. The Human Genome Project -- 14. Identifying human disease genes -- 15. Molecular pathology -- 16. Genetic testing in individuals and populations -- 17. Somatic mutations and cancer -- 18. Complex diseases -- 19. Studying human gene structure and function and creating animal models of disease -- 20. Gene therapy and other molecular genetic-based therapeutic approaches.